Volume 25, Issue 115, September 2021

Anticardiolipin antibody level in hypertensive disorders of pregnancy and its association with pregnancy outcome

Eman Kamal Abdulwahhab^1♦, Ghada Al-Sakkal²

¹Medical doctor, Hawler Maternity Hospital, Erbil, Iraq
²Assistant Prof. in Obstetrics and Gynecology, Hawler Medical College Erbil, Iraq

^♦Corresponding author
Medical doctor, Hawler Maternity Hospital, Erbil, Iraq

ABSTRACT

Objective: Find out the association of anticardiolipin antibodies between normotensive hypertensive disorders of pregnancy and pregnancy outcome, and investigate the possibility of making anticardiolipin antibodies as a biomarker for hypertensive disorders of pregnancy involving preeclampsia. Methods: A case control study conducted at maternity teaching hospital in Erbil city. The participants were selected from the obstetrical outpatient clinic or from inpatients with matching age, body mass index and gestational age. Results: Seventy-four pregnant women were enrolled in the study; 34 of them were diagnosed with hypertensive disorders of pregnancy (case group) and the other 40 were healthy pregnant women (control group). There was no statistical significance between anticardiolipin antibodies between the two main study groups, and neither between severe and non-severe hypertensive pregnant women. Hypertensive pregnant women with positive anticardiolipin antibodies had significant association with preterm delivery and neonatal weight of below 2500g (P < 0.05). Conclusions: There is an association between anticardiolipin antibody and preterm labor and low birth weight in hypertensive pregnant women.

Keywords: Hypertensive disorders of pregnancy, preeclampsia, anticardiolipin antibody

Medical Science, 2021, 25(115), 2268-2274

PDF