Volume 24, Issue 103, May - June, 2020

Comparison of almond and buckwheat oils on blood biochemical and liver function in rats with non-alcoholic fatty liver

Mozhgan Rahimi, Seyed Ebrahim Hosseini^♦, Mohammad Amin Edalatmanesh

Department of Biology, Shiraz Branch, Islamic Azad University, Shiraz, Iran

^♦Corresponding author
Department of Biology, Shiraz Branch, Islamic Azad University, Shiraz, Iran Email: Ebrahim.hosseini@yahoo.com

ABSTRACT

Introduction: almonds and buckwheat are known as useful oil seeds. So our objective was to determine the effects of their oil on the blood biochemical and liver function in rats with non-alcoholic fatty liver disease. Materials and Methods: Forty adult rats were divided into five groups. The experimental groups for 28 days were as follows; 1) control standard (normal rats), NAFL rats groups orally received 2) 1ml normal saline (control sham), 3) 1.5 ml/kg almond oil, 4) 5 ml/kg buckwheat oil, and 5) 1.5 ml/kg almond+5 ml/kg buckwheat oils. The weight of the body and liver were recorded. Liver weight was significantly higher in the high fat diet group comparing to the control groups (P<0.05). Results: Results showed that serum levels of blood urea nitrogen (BUN), creatinine, IL-6 and cholesterol were significantly lower than those in the sham groups, whereas HDL concentration was higher. Compared with control-sham groups, the administration of almond oils significantly Decrease levels of creatinine, cholesterol, and LDL. Liver enzymes, inflammatory markers and BUN levels were lower in almond and buckwheat oil supplemented rats compared to controlsham, Also, the serum concentration of HDL was markedly increased in rats fed with dietary almond and buckwheat oils treatments, although, oils supplementation were significantly reduced serum concentration of LDL and cholesterol in NAFL rats. Following almond+buckwheat oils administration, slightly decreased (P<0.05) serum levels of BUN, LDL, and IL-6 comparing to almond and buckwheat alone. Also, almond+buckwheat oils supplementation showed higher values for serum Na and K levels comparing to almond and buckwheat alone.

Keywords: Almonds, Liver enzyme, Buckwheat, Liver, Non-alcoholic fatty liver

Medical Science, 2020, 24(103), 1418-1426

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